Difference between revisions of "Part:BBa K174000"
 
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<partinfo>BBa_K174000 short</partinfo>
 
<partinfo>BBa_K174000 short</partinfo>
  
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SspB protein targets proteins tagged with modified degradation tag, ssrA, and deliver them to ClpXP for proteolysis.  Modified ssrA tags are fused onto the 3’ end of a gene.
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SspB protein targets proteins tagged with modified degradation tag, ''ssrA'', and deliver them to ClpXP for proteolysis.  Modified ''ssrA'' tags are fused onto the 3’ end of a gene.
  
 
<span class='h3bb'>Sequence and Features</span>
 
<span class='h3bb'>Sequence and Features</span>
 
<partinfo>BBa_K174000 SequenceAndFeatures</partinfo>
 
<partinfo>BBa_K174000 SequenceAndFeatures</partinfo>
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===Information contributed by City of London UK (2021)===
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Part information is collated here to help future users of the BioBrick registry.
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Metadata:
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*'''Group:''' City of London UK 2021
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*'''Author:''' Haotong Xiong
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*'''Summary:''' Added information collated from existing scientific studies
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----
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Additionally, sspB stimulates degradation of the N-terminus of RseA (residues 1-108, alone or in complex with sigma-E) by ClpXP in a non-ssrA-mediated fashion.
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<ref>“SspB - Stringent Starvation Protein B - Escherichia Coli (Strain K12) - SspB Gene & Protein.” n.d. Www.uniprot.org. https://www.uniprot.org/uniprot/P0AFZ3.</ref>

Latest revision as of 09:12, 21 September 2021

SspB proteolysis chaperone

SspB protein targets proteins tagged with modified degradation tag, ssrA, and deliver them to ClpXP for proteolysis. Modified ssrA tags are fused onto the 3’ end of a gene.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]

Information contributed by City of London UK (2021)

Part information is collated here to help future users of the BioBrick registry.

Metadata:

  • Group: City of London UK 2021
  • Author: Haotong Xiong
  • Summary: Added information collated from existing scientific studies

Additionally, sspB stimulates degradation of the N-terminus of RseA (residues 1-108, alone or in complex with sigma-E) by ClpXP in a non-ssrA-mediated fashion.

[1]
  1. ↑ “SspB - Stringent Starvation Protein B - Escherichia Coli (Strain K12) - SspB Gene & Protein.” n.d. Www.uniprot.org. https://www.uniprot.org/uniprot/P0AFZ3.