Difference between revisions of "Part:BBa K133071"
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Urease B (UreB)is one of the main ''H. pylori'' antigens. It is a subunit of enzyme urease, composed of A and B subunit that neutralizes the pH around the microorganism by decomposing urea into ammonia and carbon dioxide, thus enabling ''H. pylori'' to survive in the acidic gastric environment. Application of this antigen should elicit production of neutralizing antibodies thus inhibiting enzymatic activity of urease, which could lead to the eventual eradication of bacteria. | Urease B (UreB)is one of the main ''H. pylori'' antigens. It is a subunit of enzyme urease, composed of A and B subunit that neutralizes the pH around the microorganism by decomposing urea into ammonia and carbon dioxide, thus enabling ''H. pylori'' to survive in the acidic gastric environment. Application of this antigen should elicit production of neutralizing antibodies thus inhibiting enzymatic activity of urease, which could lead to the eventual eradication of bacteria. | ||
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Revision as of 00:21, 30 October 2008
UreB
Urease B (UreB)is one of the main H. pylori antigens. It is a subunit of enzyme urease, composed of A and B subunit that neutralizes the pH around the microorganism by decomposing urea into ammonia and carbon dioxide, thus enabling H. pylori to survive in the acidic gastric environment. Application of this antigen should elicit production of neutralizing antibodies thus inhibiting enzymatic activity of urease, which could lead to the eventual eradication of bacteria.
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21INCOMPATIBLE WITH RFC[21]Illegal BamHI site found at 1013
- 23COMPATIBLE WITH RFC[23]
- 25INCOMPATIBLE WITH RFC[25]Illegal AgeI site found at 235
Illegal AgeI site found at 1413 - 1000INCOMPATIBLE WITH RFC[1000]Illegal SapI.rc site found at 121