Difference between revisions of "Part:BBa K3450019"
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+ | __NOTOC__ | ||
+ | <partinfo>BBa_K3450019 short</partinfo> | ||
+ | CesT is a T3SS-specific multi-cargo chaperone found in E. coli [1] that interacts with multiple bacterial effectors. It was initially discovered as a chaperone of Tir (translocated intimin receptor). [2] | ||
+ | |||
+ | References | ||
+ | |||
+ | [1] Thomas, N. A. et al. CesT is a multi-effector chaperone and recruitment factor required for the efficient type III secretion of both LEE- and non-LEE-encoded effectors of enteropathogenic Escherichia coli. 57, 1762–1779 (2005). | ||
+ | [2] Ye, F., Yang, F., Yu, R. et al. Molecular basis of binding between the global post-transcriptional regulator CsrA and the T3SS chaperone CesT. Nat Commun 9, 1196 (2018). | ||
+ | |||
+ | <!-- Add more about the biology of this part here | ||
+ | ===Usage and Biology=== | ||
+ | |||
+ | <!-- --> | ||
+ | <span class='h3bb'>Sequence and Features</span> | ||
+ | <partinfo>BBa_K3450019 SequenceAndFeatures</partinfo> | ||
+ | |||
+ | |||
+ | <!-- Uncomment this to enable Functional Parameter display | ||
+ | ===Functional Parameters=== | ||
+ | <partinfo>BBa_K3450019 parameters</partinfo> | ||
+ | <!-- --> |
Latest revision as of 16:40, 26 October 2020
CesT: Type-3 secretion system substrate chaperone
CesT is a T3SS-specific multi-cargo chaperone found in E. coli [1] that interacts with multiple bacterial effectors. It was initially discovered as a chaperone of Tir (translocated intimin receptor). [2]
References
[1] Thomas, N. A. et al. CesT is a multi-effector chaperone and recruitment factor required for the efficient type III secretion of both LEE- and non-LEE-encoded effectors of enteropathogenic Escherichia coli. 57, 1762–1779 (2005). [2] Ye, F., Yang, F., Yu, R. et al. Molecular basis of binding between the global post-transcriptional regulator CsrA and the T3SS chaperone CesT. Nat Commun 9, 1196 (2018).
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21INCOMPATIBLE WITH RFC[21]Illegal BglII site found at 104
Illegal BglII site found at 203
Illegal XhoI site found at 199 - 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]