Difference between revisions of "Part:BBa K3647777"
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<span class='h3bb'><h1>Sequence and Features</h1></span>
 
<span class='h3bb'><h1>Sequence and Features</h1></span>
 
<partinfo>BBa_K3647777 SequenceAndFeatures</partinfo>
 
<partinfo>BBa_K3647777 SequenceAndFeatures</partinfo>
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<h1>General information</h1>
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Histamine N-methyltransferase is one of the two enzymes involved in the metabolism of histamine in mammals, this is known as the N(tau)-methylation pathway. The second pathway is oxidative deamination via diamine oxidase (DAO). This protein is encoded by the gene HNMT and it can be found in the cytosol intracellular fluid. HNMT is expressed in many organs like liver, kidney and brain, being found in most of the body tissues, except for serum.
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([https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386932// Yoshikawa, 2019])
  
  
 
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===Usage and Biology===
 
===Usage and Biology===
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Revision as of 08:40, 18 October 2020

Histamine N-methyltransferase (N-term. 6XHIS, TEV)


For information and characterization of this part please see: BBa_K3647666

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    INCOMPATIBLE WITH RFC[21]
    Illegal BamHI site found at 40
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    INCOMPATIBLE WITH RFC[1000]
    Illegal BsaI.rc site found at 394
    Illegal BsaI.rc site found at 778

General information

Histamine N-methyltransferase is one of the two enzymes involved in the metabolism of histamine in mammals, this is known as the N(tau)-methylation pathway. The second pathway is oxidative deamination via diamine oxidase (DAO). This protein is encoded by the gene HNMT and it can be found in the cytosol intracellular fluid. HNMT is expressed in many organs like liver, kidney and brain, being found in most of the body tissues, except for serum. (Yoshikawa, 2019)