Difference between revisions of "Part:BBa K3113051"
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Based on SWISS-MODEL, a protein structure homology-modelling server, we were able to model CD63 and to search for sites within CD63 that are accessible. | Based on SWISS-MODEL, a protein structure homology-modelling server, we were able to model CD63 and to search for sites within CD63 that are accessible. | ||
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<h3>6 histidines were added after position Ser161 based on a structural model for CD63 generated with swissmodel.expasy.org</h3> | <h3>6 histidines were added after position Ser161 based on a structural model for CD63 generated with swissmodel.expasy.org</h3> | ||
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| + | <!-- Add more about the biology of this part here | ||
| + | ===Usage and Biology=== | ||
Revision as of 11:41, 20 October 2019
CD63_Ser161_6xHis
To facilitate the purification of intact exosomes, we engineered the exosomal marker CD63 by integrating a polyhistidine repeat into the large extracellular loop of the tetraspanin. Based on SWISS-MODEL, a protein structure homology-modelling server, we were able to model CD63 and to search for sites within CD63 that are accessible.
6 histidines were added after position Ser161 based on a structural model for CD63 generated with swissmodel.expasy.org
<figure class="figure">
<img src="
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Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]