Difference between revisions of "Part:BBa K3182006"

Revision as of 10:44, 7 October 2019

Magainin 2

African Clawed Frog antimicrobial peptide Magainin-2. Designed to target bacteria, virus and fungus. The peptide is 24 amino acids long and carries mostly hydrophobic residues. The four lysines present provide a slight positive charge. Magainin-2 mimics membrane protein by having a single alpha helix which will interact with the lipid membrane of bacteria.

The peptide is designed to battle the Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, Enterobacter spp. family of pathogens (ESKAPE). ESKAPE is a family(ies) of bacteria which has multiple understrains that has evolved resistance to the most commonly used antibiotics.. This part was designed to be assembled with BBa_K3182100.

Sequence and Features

Assembly Compatibility:

10
COMPATIBLE WITH RFC[10]
12
COMPATIBLE WITH RFC[12]
21
COMPATIBLE WITH RFC[21]
23
COMPATIBLE WITH RFC[23]
25
COMPATIBLE WITH RFC[25]
1000
COMPATIBLE WITH RFC[1000]

@@ Line 3: / Line 3: @@
 <partinfo>BBa_K3182006 short</partinfo>
-African Clawed Frog antimicrobial peptide. Designed to target bacteria, virus and fungus. This part was designed to be assembled with BBa_K3182100.
+African Clawed Frog antimicrobial peptide Magainin-2. Designed to target bacteria, virus and fungus. The peptide is 24 amino acids long and carries mostly hydrophobic residues. The four lysines present provide a slight positive charge. Magainin-2 mimics membrane protein by having a single alpha helix which will interact with the lipid membrane of bacteria.
+The peptide is designed to battle the Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, Enterobacter spp. family of pathogens (ESKAPE). ESKAPE is a family(ies) of bacteria which has multiple understrains that has evolved resistance to the most commonly used antibiotics.. This part was designed to be assembled with BBa_K3182100.