Difference between revisions of "Part:BBa K2832000"
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<partinfo>BBa_K2832000 short</partinfo> | <partinfo>BBa_K2832000 short</partinfo> | ||
− | + | The bamEp promoter upregulates the bamE gene which is responsible for the aggregation of outer membrane proteins and membrane permeability by production of protein BamE. This promoter is activated by RpoE, the sigma 24 factor of RNA polymerase. Since RpoE is activated by external stress on the plasma membrane, it activates regulatory genes such as bamE to respond to extracellular stress. Stresses include misfolding, heat shock, and osmotic shock of outer membrane proteins, and structural changes to the membranous lipopolysaccharides. | |
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Revision as of 04:16, 3 December 2018
PbamE - Inducible Promoter
The bamEp promoter upregulates the bamE gene which is responsible for the aggregation of outer membrane proteins and membrane permeability by production of protein BamE. This promoter is activated by RpoE, the sigma 24 factor of RNA polymerase. Since RpoE is activated by external stress on the plasma membrane, it activates regulatory genes such as bamE to respond to extracellular stress. Stresses include misfolding, heat shock, and osmotic shock of outer membrane proteins, and structural changes to the membranous lipopolysaccharides.
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25INCOMPATIBLE WITH RFC[25]Illegal NgoMIV site found at 13
- 1000COMPATIBLE WITH RFC[1000]