Difference between revisions of "Part:BBa K2534003:Design"

 
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__NOTOC__
 
__NOTOC__
 
<partinfo>BBa_K2534003 short</partinfo>
 
<partinfo>BBa_K2534003 short</partinfo>
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miRNA-134 5p has been discovered to function as tumor suppressors in colorectal cancer by independently suppressing EGFR and PI3K signalling.
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[http://2018.igem.org/Team:AFCM-Egypt# Team:AFCM-Egypt 2018] worked to do lentiviral transfection of that part into colorectal cancer cell line RKO to induce regulatory apoptosis as well as to investigate it's immune modulatory effect on TLR-9.
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[http://2018.igem.org/Team:AFCM-Egypt# Team:AFCM-Egypt 2018] have characterized this part considering it's apoptotic effect of RKO cell lines.
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For further information about demonstration of its apoptotic effect, please visit our results page
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http://2018.igem.org/Team:AFCM-Egypt/Demonstrate
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https://static.igem.org/mediawiki/parts/5/51/Chmir134afcm.png
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<partinfo>BBa_K2534003 SequenceAndFeatures</partinfo>
 
<partinfo>BBa_K2534003 SequenceAndFeatures</partinfo>
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===Design Notes===
 
===Design Notes===
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IDT
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This part has been synthesized through IDT offer
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===Source===
 
===Source===
  
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IDT
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http://2018.igem.org/Team:AFCM-Egypt/Bioinformatics_Page_link
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===References===
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Revision as of 12:19, 17 October 2018


miRNA 134 5p


miRNA-134 5p has been discovered to function as tumor suppressors in colorectal cancer by independently suppressing EGFR and PI3K signalling. [http://2018.igem.org/Team:AFCM-Egypt# Team:AFCM-Egypt 2018] worked to do lentiviral transfection of that part into colorectal cancer cell line RKO to induce regulatory apoptosis as well as to investigate it's immune modulatory effect on TLR-9. [http://2018.igem.org/Team:AFCM-Egypt# Team:AFCM-Egypt 2018] have characterized this part considering it's apoptotic effect of RKO cell lines.

For further information about demonstration of its apoptotic effect, please visit our results page http://2018.igem.org/Team:AFCM-Egypt/Demonstrate


Chmir134afcm.png



Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


Design Notes

This part has been synthesized through IDT offer


Source

http://2018.igem.org/Team:AFCM-Egypt/Bioinformatics_Page_link