Difference between revisions of "Part:BBa K2588011"
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<h2>Usage and Biology</h2> | <h2>Usage and Biology</h2> | ||
| − | <p>The Acetyl-CoA carboxyl carrier protein is part of the acetyl-CoA carboxylase ACC, which is the major regulator for fatty acid biosynthesis in e. coli. It is encoded as a single mRNA with the downstream accC, which is encoding for the biotin carboxylase of the complex.<sup>1</sup> The acetyl-CoA biotin carboxyl carrier protein binds with biotin and transfers carboxylated biotin to the acetyl-CoA carboxyltransferase.<sup>2</sup> | + | <p>The Acetyl-CoA biotin carboxyl carrier protein is part of the acetyl-CoA carboxylase ACC, which is the major regulator for fatty acid biosynthesis in e. coli. It is encoded as a single mRNA with the downstream accC, which is encoding for the biotin carboxylase of the complex.<sup>1</sup> The acetyl-CoA biotin carboxyl carrier protein binds with biotin and transfers carboxylated biotin to the acetyl-CoA carboxyltransferase.<sup>2</sup> |
</p> | </p> | ||
| + | <p>The acetyl-CoA biotin carboxyl carrier protein was used in our myristic acid synthesis module, <a href="https://parts.igem.org/Part:BBa_K2588022">BBa_K2588022</a>.</p> | ||
<h2>References</h2> | <h2>References</h2> | ||
Revision as of 11:00, 17 October 2018
Acetyl-CoA biotin carboxyl carrier protein
Usage and Biology
The Acetyl-CoA biotin carboxyl carrier protein is part of the acetyl-CoA carboxylase ACC, which is the major regulator for fatty acid biosynthesis in e. coli. It is encoded as a single mRNA with the downstream accC, which is encoding for the biotin carboxylase of the complex.1 The acetyl-CoA biotin carboxyl carrier protein binds with biotin and transfers carboxylated biotin to the acetyl-CoA carboxyltransferase.2
The acetyl-CoA biotin carboxyl carrier protein was used in our myristic acid synthesis module, BBa_K2588022.
References
- Li, S. J. & Cronan, J. E. The gene encoding the biotin carboxylase subunit of Escherichia coli acetyl-CoA carboxylase. J. Biol. Chem. 267, 855–63 (1992).
- Broussard, T. C., Price, A. E., Laborde, S. M. & Waldrop, G. L. Complex formation and regulation of escherichia coli acetyl-CoA carboxylase. Biochemistry (2013). doi:10.1021/bi4000707
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25INCOMPATIBLE WITH RFC[25]Illegal AgeI site found at 432
- 1000COMPATIBLE WITH RFC[1000]