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| | __NOTOC__ | | __NOTOC__ |
| | <partinfo>BBa_K2862006 short</partinfo> | | <partinfo>BBa_K2862006 short</partinfo> |
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| − | SoxR from E. coli (new)
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| − | SoxR is a redox-sensitive transcription factor providing transcriptional activation or repression downstream of the pSoxS promoter when oxidised, either directly by redox-cycling drugs or by oxidative stress. It is therefore inducible by various redox-cycling drugs, toxins, antibiotics, heavy metals, hydrogen peroxide and nitric oxide: providing various applications in the development of environmental and therapeutic devices. By coupling oxidation of redox-cycling species to an electrode, the 2018 Imperial College London iGEM team (PixCell) used SoxR to build electrogenetic devices where electrical inputs modulated gene expression.
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| − | This SoxR CDS was taken from X, and is codon optimised for E. coli. It forms part of the PixCell library of electrogenetic and redox-sensing parts.
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| − | This part has been designed to be fully modular, being compatible for BioBrick, BASIC and Golden Gate assembly.
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