Difference between revisions of "Part:BBa K2729013"

 
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<partinfo>BBa_K2729013 short</partinfo>
 
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==Usage and Biology==
 
Flavivirus Capsid (C), prM (precursor Membrane) and Envelope (E) are structural proteins responsible for gathering the viral RNA into a nucleocapsid that forms the core of a mature virus particle.
 
Flavivirus Capsid (C), prM (precursor Membrane) and Envelope (E) are structural proteins responsible for gathering the viral RNA into a nucleocapsid that forms the core of a mature virus particle.
  
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==Characterization==
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===Usage and Biology===
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The prM protein consists of an N-terminal pr domain followed by the M protein separated by a furin cleavage site.(15) The pr part of the protein consists mainly of β-strands, whereas the M portion consists of a linear structure followed by a mainly α-helical stem region and two transmembrane helices.
  
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==Sequence and Features==
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<span class='h3bb'>Sequence and Features</span>
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<partinfo>BBa_K2729013 SequenceAndFeatures</partinfo>
 
<partinfo>BBa_K2729013 SequenceAndFeatures</partinfo>
  
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==Reference==
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- [https://pubs.acs.org/doi/10.1021/bi500724k Membranotropic regions of the dengue virus prM protein]
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===Functional Parameters===
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<partinfo>BBa_K2729013 parameters</partinfo>
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Revision as of 14:34, 16 October 2018


DENV4 ancC-prM-E (Dengue Virus Serotype IV)

Usage and Biology

Flavivirus Capsid (C), prM (precursor Membrane) and Envelope (E) are structural proteins responsible for gathering the viral RNA into a nucleocapsid that forms the core of a mature virus particle.

Characterization

The prM protein consists of an N-terminal pr domain followed by the M protein separated by a furin cleavage site.(15) The pr part of the protein consists mainly of β-strands, whereas the M portion consists of a linear structure followed by a mainly α-helical stem region and two transmembrane helices.

Sequence and Features


Assembly Compatibility:
  • 10
    INCOMPATIBLE WITH RFC[10]
    Illegal EcoRI site found at 488
    Illegal EcoRI site found at 1947
    Illegal SpeI site found at 1219
  • 12
    INCOMPATIBLE WITH RFC[12]
    Illegal EcoRI site found at 488
    Illegal EcoRI site found at 1947
    Illegal SpeI site found at 1219
  • 21
    INCOMPATIBLE WITH RFC[21]
    Illegal EcoRI site found at 488
    Illegal EcoRI site found at 1947
    Illegal BamHI site found at 1910
  • 23
    INCOMPATIBLE WITH RFC[23]
    Illegal EcoRI site found at 488
    Illegal EcoRI site found at 1947
    Illegal SpeI site found at 1219
  • 25
    INCOMPATIBLE WITH RFC[25]
    Illegal EcoRI site found at 488
    Illegal EcoRI site found at 1947
    Illegal SpeI site found at 1219
    Illegal NgoMIV site found at 1207
  • 1000
    INCOMPATIBLE WITH RFC[1000]
    Illegal SapI.rc site found at 793

Reference

- Membranotropic regions of the dengue virus prM protein