Difference between revisions of "Part:BBa K2548011:Design"

 
 
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===Design Notes===
 
===Design Notes===
−
N/A.
 
  
 +
As an antimicrobial peptide that is not homologous to any AMPs currently known, cPcAMP1, is identified from <i>Paramecium Caudatum</i> and is able to treat <I>A. hydrophila</i>. The cPcAMP1 has the capacity to increase the permeability of bacterial cell membrane and depolarize bacterial cells. Furthermore, the cPcAMP1 is not toxic to eukaryotic cells so when it is applied to the fishes, it causes no harm.
  
  
 
===Source===
 
===Source===
  
−
Paramecium caudatum
+
Cui, P., Dong, Y., Li, Z., Zhang, Y., & Zhang, S. (2016). Identification and functional characterization of an uncharacterized antimicrobial peptide from a ciliate Paramecium caudatum. Developmental & Comparative Immunology,60, 53-65. doi:10.1016/j.dci.2016.02.016
  
 
===References===
 
===References===

Latest revision as of 14:20, 16 October 2018


LacI - pTac - cPcAMP1 + 6xHis Tag - Terminator


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


Design Notes

As an antimicrobial peptide that is not homologous to any AMPs currently known, cPcAMP1, is identified from Paramecium Caudatum and is able to treat A. hydrophila. The cPcAMP1 has the capacity to increase the permeability of bacterial cell membrane and depolarize bacterial cells. Furthermore, the cPcAMP1 is not toxic to eukaryotic cells so when it is applied to the fishes, it causes no harm.


Source

Cui, P., Dong, Y., Li, Z., Zhang, Y., & Zhang, S. (2016). Identification and functional characterization of an uncharacterized antimicrobial peptide from a ciliate Paramecium caudatum. Developmental & Comparative Immunology,60, 53-65. doi:10.1016/j.dci.2016.02.016

References