Difference between revisions of "Part:BBa K2607001"
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<partinfo>BBa_K2607001 short</partinfo> | <partinfo>BBa_K2607001 short</partinfo> | ||
− | + | This part is a chimeric between extracellular (binding) domain of <i>Homo sapiens</i> heparin-binding EGF-like growth factor (HB-EGF) receptor and transmembrane/intracellular domain of <i>Escherichia coli</i> Tar chemotaxis receptor. | |
− | |||
===Usage and Biology=== | ===Usage and Biology=== | ||
+ | This part can be used to detect diphtheria toxin as it has HB-EGF binding domain. It also can activate chemotaxis pathway in <i>E. coli</i> upon receptor activation as it has Tar transmembrane/intracellular domain. | ||
− | |||
<span class='h3bb'>Sequence and Features</span> | <span class='h3bb'>Sequence and Features</span> | ||
<partinfo>BBa_K2607001 SequenceAndFeatures</partinfo> | <partinfo>BBa_K2607001 SequenceAndFeatures</partinfo> |
Latest revision as of 03:36, 15 October 2018
HB-EGF/Tar Receptor (HT) Device
This part is a chimeric between extracellular (binding) domain of Homo sapiens heparin-binding EGF-like growth factor (HB-EGF) receptor and transmembrane/intracellular domain of Escherichia coli Tar chemotaxis receptor.
Usage and Biology
This part can be used to detect diphtheria toxin as it has HB-EGF binding domain. It also can activate chemotaxis pathway in E. coli upon receptor activation as it has Tar transmembrane/intracellular domain.
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25INCOMPATIBLE WITH RFC[25]Illegal AgeI site found at 1294
- 1000INCOMPATIBLE WITH RFC[1000]Illegal BsaI site found at 1434