Difference between revisions of "Part:BBa K2534003"
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<partinfo>BBa_K2534003 short</partinfo> | <partinfo>BBa_K2534003 short</partinfo> | ||
− | miRNA 134 5p | + | miRNA-134 5p has been discovered to function as tumor suppressors in colorectal cancer by independently suppressing EGFR and PI3K signalling. |
+ | [http://2018.igem.org/Team:AFCM-Egypt# Team:AFCM-Egypt 2018] worked to do lentiviral transfection of that part into colorectal cancer cell line RKO to induce regulatory apoptosis as well as to investigate it's immune modulatory effect on TLR-9 | ||
+ | |||
<!-- Add more about the biology of this part here | <!-- Add more about the biology of this part here |
Revision as of 22:09, 14 October 2018
miRNA 134 5p
miRNA-134 5p has been discovered to function as tumor suppressors in colorectal cancer by independently suppressing EGFR and PI3K signalling. [http://2018.igem.org/Team:AFCM-Egypt# Team:AFCM-Egypt 2018] worked to do lentiviral transfection of that part into colorectal cancer cell line RKO to induce regulatory apoptosis as well as to investigate it's immune modulatory effect on TLR-9
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]