Difference between revisions of "Part:BBa K2374007"
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Revision as of 17:24, 31 October 2017
UAS-TH -> (fruit fly)
ple (Tyrosine 3-monooxygenase, TH)
ple (TH) is a rate-limiting enzyme in the dopamine’s synthesis, and it plays an important role in the physiology of adrenergic neurons.
Catalytic activity:
L-tyrosine + tetrahydrobiopterin + O2 = L-dopa + 4a-hydroxytetrahydrobiopterin.
This subpathway is part of the pathway dopamine biosynthesis, which is itself part of catecholamine biosynthesis.