Difference between revisions of "Part:BBa K2279000"
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<span class='h3bb'>Sequence and Features</span>
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===Usage and Biology===
 
===Usage and Biology===
 
The <i>B.subtilis</i> bacteriophage phi3T encode the Aim system to make lysis-lysogeny decision. The AimR is a transcription factor, the AimP is the propeptide of the mature signal peptide. However, binding of AimP to the AimR will disrupt the dimer forms of AimR, which will dissociate the AimR dimer. After that, the AimR can no longer bind to the promoter of AimX, a potential non coding RNA involved in the process of lysis-lysogeny.  
 
The <i>B.subtilis</i> bacteriophage phi3T encode the Aim system to make lysis-lysogeny decision. The AimR is a transcription factor, the AimP is the propeptide of the mature signal peptide. However, binding of AimP to the AimR will disrupt the dimer forms of AimR, which will dissociate the AimR dimer. After that, the AimR can no longer bind to the promoter of AimX, a potential non coding RNA involved in the process of lysis-lysogeny.  
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===Reference===
 
===Reference===
 
Erez, Z., Steinberger-Levy, I., Shamir, M., Doron, S., Stokar-Avihail, A., Peleg, Y., Melamed, S., Leavitt, A., Savidor, A., Albeck, S., et al. (2017). Communication between viruses guides lysis-lysogeny decisions. Nature 541, 488-493.
 
Erez, Z., Steinberger-Levy, I., Shamir, M., Doron, S., Stokar-Avihail, A., Peleg, Y., Melamed, S., Leavitt, A., Savidor, A., Albeck, S., et al. (2017). Communication between viruses guides lysis-lysogeny decisions. Nature 541, 488-493.
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===Functional Parameters===
 
===Functional Parameters===
 
<partinfo>BBa_K2279000 parameters</partinfo>
 
<partinfo>BBa_K2279000 parameters</partinfo>
 
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Revision as of 12:25, 25 October 2017


AimR

AimR is a transcription factor.


Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    INCOMPATIBLE WITH RFC[1000]
    Illegal SapI site found at 429
    Illegal SapI.rc site found at 169
    Illegal SapI.rc site found at 492

Usage and Biology

The B.subtilis bacteriophage phi3T encode the Aim system to make lysis-lysogeny decision. The AimR is a transcription factor, the AimP is the propeptide of the mature signal peptide. However, binding of AimP to the AimR will disrupt the dimer forms of AimR, which will dissociate the AimR dimer. After that, the AimR can no longer bind to the promoter of AimX, a potential non coding RNA involved in the process of lysis-lysogeny. Aim.jpeg

Reference

Erez, Z., Steinberger-Levy, I., Shamir, M., Doron, S., Stokar-Avihail, A., Peleg, Y., Melamed, S., Leavitt, A., Savidor, A., Albeck, S., et al. (2017). Communication between viruses guides lysis-lysogeny decisions. Nature 541, 488-493.