Difference between revisions of "Part:BBa K2215003"

Revision as of 06:04, 1 October 2017

CuZn SOD

Superoxide dismutases (SOD) are the first line of defense against reactive oxygen species when cells become stressed. This makes them important antioxidants in the cell that is responsible for converting superoxide anion radicals into hydrogen peroxide, which can be further converted into water. (Alscher et al., 2002) There are different types of SODs in the cell, but this one is known as copper-zinc SOD (CuZn-SOD) that resides in the cytosol, chloroplast, and extracellular space. This gene was taken from BBa_K1456003 by iGEM14_ATOMS-Turkiye and was codon optimized for Chlamydomonas. As such, this gene is characterized in Chlamydomonas and should be used in Chlamydomonas or should be optimized for the specific species that is to be used.

Sequence and Features

Assembly Compatibility:

10
COMPATIBLE WITH RFC[10]
12
COMPATIBLE WITH RFC[12]
21
COMPATIBLE WITH RFC[21]
23
COMPATIBLE WITH RFC[23]
25
COMPATIBLE WITH RFC[25]
1000
COMPATIBLE WITH RFC[1000]

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 <partinfo>BBa_K2215003 short</partinfo>
-CuZn Superoxide Dismutase (CuZn-SOD) was taken from BBa_K1456003 by iGEM14_ATOMS-Turkiye and was codon optimized for Chlamydomonas. CuZn-SOD is an important antioxidant that resides in the cytosol of the cell and is responsible for converting superoxide anion radicals into hydrogen peroxide. This gene is characterized specifically for Chlamydomonas and should only be used in chlamydomonas, or should be optimized for the specific species that is to be used.
+Superoxide dismutases (SOD) are the first line of defense against reactive oxygen species when cells become stressed. This makes them important antioxidants in the cell that is responsible for converting superoxide anion radicals into hydrogen peroxide, which can be further converted into water. (Alscher et al., 2002)
+There are different types of SODs in the cell, but this one is known as copper-zinc SOD (CuZn-SOD) that resides in the cytosol, chloroplast, and extracellular space.
+This gene was taken from BBa_K1456003 by iGEM14_ATOMS-Turkiye and was codon optimized for Chlamydomonas. As such, this gene is characterized in Chlamydomonas and should be used in Chlamydomonas or should be optimized for the specific species that is to be used.
 <!-- Add more about the biology of this part here