Difference between revisions of "Part:BBa K209472"
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<partinfo>BBa_K209472 short</partinfo> | <partinfo>BBa_K209472 short</partinfo> | ||
+ | This is the coding sequence of Homo sapiens adrenoceptor beta 2 (ADRB2). This part has been improved by SJTU-Biox-Shanghai 2016 iGEM team to generate two parts with modified sequence: BBa_K1969001 and BBa_K1969002. | ||
+ | BBa_K1969001 | ||
+ | Group: SJTU-Biox-Shanghai 2016 | ||
+ | Author: Yijie Lai | ||
+ | Summary: This improved version using site mutation to eliminate the illegal PstI site by changing G at 192 bp to A, and was tested for epinephrine response when expressed in yeast Saccharomyces cerevisiae under two different promoters, GAL1 and ADH1. | ||
+ | |||
+ | BBa_K1969002 | ||
+ | Group: SJTU-Biox-Shanghai 2016 | ||
+ | Author: Yijie Lai | ||
+ | Summary: This improved version using site mutation to eliminate the illegal PstI site by changing G at 192 bp to A and adding a his-tag to its C terminus. The sequence was tested for membrane localization when expressed in yeast Saccharomyces cerevisiae under two different promoters, GAL1 and ADH1. | ||
Latest revision as of 05:13, 27 October 2016
AarI B-D part, ADRA2A (B2AR)
This is the coding sequence of Homo sapiens adrenoceptor beta 2 (ADRB2). This part has been improved by SJTU-Biox-Shanghai 2016 iGEM team to generate two parts with modified sequence: BBa_K1969001 and BBa_K1969002.
BBa_K1969001 Group: SJTU-Biox-Shanghai 2016 Author: Yijie Lai Summary: This improved version using site mutation to eliminate the illegal PstI site by changing G at 192 bp to A, and was tested for epinephrine response when expressed in yeast Saccharomyces cerevisiae under two different promoters, GAL1 and ADH1.
BBa_K1969002 Group: SJTU-Biox-Shanghai 2016 Author: Yijie Lai Summary: This improved version using site mutation to eliminate the illegal PstI site by changing G at 192 bp to A and adding a his-tag to its C terminus. The sequence was tested for membrane localization when expressed in yeast Saccharomyces cerevisiae under two different promoters, GAL1 and ADH1.
Sequence and Features
- 10INCOMPATIBLE WITH RFC[10]Illegal PstI site found at 190
- 12INCOMPATIBLE WITH RFC[12]Illegal PstI site found at 190
- 21INCOMPATIBLE WITH RFC[21]Illegal BglII site found at 778
- 23INCOMPATIBLE WITH RFC[23]Illegal PstI site found at 190
- 25INCOMPATIBLE WITH RFC[25]Illegal PstI site found at 190
- 1000INCOMPATIBLE WITH RFC[1000]Illegal BsaI.rc site found at 364
Illegal BsaI.rc site found at 562