Difference between revisions of "Part:BBa K1930004"

 
Line 3: Line 3:
 
<partinfo>BBa_K1930004 short</partinfo>
 
<partinfo>BBa_K1930004 short</partinfo>
  
−
QnrS1 resistance cassette BioBrick BBa_K1930004.
+
This part is a fluoroquinolone resistance gene <em>qnrS1</em>. This gene is found naturally in <em>E. coli</em>, and other Gram-negative strains. <em>qnr</em> genes code for pentapeptide repeat proteins. These proteins reduce susceptibility to quinolones by protecting the complex of DNA and DNA gyrase enzyme from the inhibitory effect of quinolones. 
  
 
<!-- Add more about the biology of this part here
 
<!-- Add more about the biology of this part here

Revision as of 23:21, 16 October 2016


Ciprofloxacin resistance cassette

This part is a fluoroquinolone resistance gene qnrS1. This gene is found naturally in E. coli, and other Gram-negative strains. qnr genes code for pentapeptide repeat proteins. These proteins reduce susceptibility to quinolones by protecting the complex of DNA and DNA gyrase enzyme from the inhibitory effect of quinolones. 

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    INCOMPATIBLE WITH RFC[21]
    Illegal BglII site found at 536
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]