Difference between revisions of "Part:BBa K1993001"
LittleCloud (Talk | contribs) |
LittleCloud (Talk | contribs) |
||
| Line 7: | Line 7: | ||
| − | + | <html> | |
| + | <img src="https://static.igem.org/mediawiki/2016/9/9d/T--SYSU-MEDICINE--Chemokine_receptors.png" style="width:400px" ></a> | ||
| + | |||
| + | |||
| + | </html> | ||
| + | |||
'''Figure 1. typical structure of a chemokine receptor.''' | '''Figure 1. typical structure of a chemokine receptor.''' | ||
Revision as of 16:07, 15 October 2016
CCR7
Chemokine receptors are found on the surface of certain cells that interact with chemokines. They have a 7-transmembrane (7TM) structure and couples to G-protein for signal transduction within a cell[1] (Figure 1). Following interaction with their specific chemokine ligands, chemokine receptors trigger a flux inintracellular calcium (Ca2+) ions which initiate the onset of chemotaxis that traffics the cell to a desired location (Figure 2).
Figure 1. typical structure of a chemokine receptor.
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000INCOMPATIBLE WITH RFC[1000]Illegal BsaI.rc site found at 1111
Illegal SapI site found at 1017