Difference between revisions of "Part:BBa K135000"

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<partinfo>BBa_K135000 short</partinfo>
 
<partinfo>BBa_K135000 short</partinfo>
  
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This is an adhesion responsive promoter (specifically adhesion to hydrophobic surfaces), and can be used to upregulate downstream gene expression in response to adhesion to such surfaces. It contains the binding site for CpxR-P (phosphorylated CpxR). CpxR is one member of the two-component Cpx response to envelope stress. Briefly, envelope stress causes CpxA, an inner-membrane histidine Kinase to Phosphorylate CpxR, allowing it to bind to CpxR-P responsive regions and regulate downstream target genes. See 'Surface sensing and adhesion of Escherichia coli controlled by the Cpx-signaling pathway', Karen Otto and Thomas J. Silhavy, PNAS, Vol. 99., No, 4., 2287-2292. 2002.  
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This is an adhesion responsive promoter (specifically adhesion to hydrophobic surfaces), and can be used to upregulate downstream gene expression in response to adhesion to such surfaces. It contains the binding site for CpxR-P (phosphorylated CpxR). CpxR is one member of the two-component Cpx response to envelope stress. Briefly, envelope stress causes CpxA, an inner-membrane histidine Kinase to Phosphorylate CpxR, allowing it to bind to CpxR-P responsive regions and regulate downstream target genes. See [[Part:BBa_K135000:Design | references]] for further information.
  
 
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===Functional Parameters===
 
===Functional Parameters===
 
<partinfo>BBa_K135000 parameters</partinfo>
 
<partinfo>BBa_K135000 parameters</partinfo>
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Latest revision as of 11:48, 15 October 2016

pCpxR (CpxR responsive promoter)

This is an adhesion responsive promoter (specifically adhesion to hydrophobic surfaces), and can be used to upregulate downstream gene expression in response to adhesion to such surfaces. It contains the binding site for CpxR-P (phosphorylated CpxR). CpxR is one member of the two-component Cpx response to envelope stress. Briefly, envelope stress causes CpxA, an inner-membrane histidine Kinase to Phosphorylate CpxR, allowing it to bind to CpxR-P responsive regions and regulate downstream target genes. See references for further information.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


Functional Parameters

negative_regulators-NA-
positive_regulators1