Difference between revisions of "Part:BBa K1590001"

Revision as of 20:52, 18 September 2015

Human Haemoglobin B

Human haemoglobin (hemoglobin) forms a tetramer consisting of two A-chains and two B-chains. This biobrick is a synthetic gene encoding the human haemoglobin B-chain that has been optimized for expression in E. coli.

Usage and Biology

Haemoglobin is the tetrameric protein molecule in red blood cells that carries oxygen. It is composed of four polypeptide chains, which in adults consist of two alpha (A) globin chains and two beta (B) globin chains. The protein also normally contains the iron-containing cofactor haem (or heme). Haemoglobin can still be found free in the blood plasma at a concentration of up to 0.1 g/l.

••••

iGEM Dundee 2015

This synthetic gene was found to produce stable product when expressed in E. coli cells.

Results

Sequence and Features

Assembly Compatibility:

10
COMPATIBLE WITH RFC[10]
12
COMPATIBLE WITH RFC[12]
21
COMPATIBLE WITH RFC[21]
23
COMPATIBLE WITH RFC[23]
25
COMPATIBLE WITH RFC[25]
1000
COMPATIBLE WITH RFC[1000]

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 Haemoglobin is the tetrameric protein molecule in red blood cells that carries oxygen. It is composed of four polypeptide chains, which in adults consist of two alpha (A) globin chains and two beta (B) globin chains. The protein also normally contains the iron-containing cofactor haem (or heme). Haemoglobin can still be found free in the blood plasma at a concentration of up to 0.1 g/l.
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+|-
+|width='10%'|
+<partinfo>BBa_K562000 AddReview 4</partinfo>
+<I>iGEM Dundee 2015</I>
+|width='60%' valign='top'|
+This synthetic gene was found to produce stable product when expressed in <i>E. coli</i> cells.
+|}
+;
 ===Results===