Difference between revisions of "Part:BBa K1745002"
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− | Expression and possibly secretion of enzyme AANAT (aralkylamine N-acetyltransferase) [ Homo sapiens (human) ]. AANAT catalyzes Serotonin into N-acetylserotonin, a Melatonin precursor, and it is the rate-limiting step in Melatonin production. (Zheng 2002) Melatonin (N-acetyl-5-methoxytryptamine) is | + | Expression and possibly secretion of enzyme AANAT (aralkylamine N-acetyltransferase) [ Homo sapiens (human) ]. AANAT catalyzes Serotonin into N-acetylserotonin, a Melatonin precursor, and it is the rate-limiting step in Melatonin production. (Zheng 2002) Melatonin (N-acetyl-5-methoxytryptamine) is responsible for regulating circadian rhythms such as the sleep cycle and seasonal behaviors such as color change and reproduction in animals.(Lincoln 2003) In humans, AANAT is secreted in the Pineal gland. This construct is His-tagged. |
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Latest revision as of 19:49, 18 September 2015
AANAT Expression
Expression and possibly secretion of enzyme AANAT (aralkylamine N-acetyltransferase) [ Homo sapiens (human) ]. AANAT catalyzes Serotonin into N-acetylserotonin, a Melatonin precursor, and it is the rate-limiting step in Melatonin production. (Zheng 2002) Melatonin (N-acetyl-5-methoxytryptamine) is responsible for regulating circadian rhythms such as the sleep cycle and seasonal behaviors such as color change and reproduction in animals.(Lincoln 2003) In humans, AANAT is secreted in the Pineal gland. This construct is His-tagged.
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12INCOMPATIBLE WITH RFC[12]Illegal NheI site found at 7
Illegal NheI site found at 30 - 21INCOMPATIBLE WITH RFC[21]Illegal BamHI site found at 115
- 23COMPATIBLE WITH RFC[23]
- 25INCOMPATIBLE WITH RFC[25]Illegal NgoMIV site found at 509
- 1000COMPATIBLE WITH RFC[1000]