Difference between revisions of "Part:BBa K1590008"

 
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<partinfo>BBa_K1590008 short</partinfo>
 
<partinfo>BBa_K1590008 short</partinfo>
  
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Coding sequence for Lactoferrin Binding Protein of Neisseria Meningitidis. This protein sequesters Iron for the host from Lactoferrin.
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Coding sequence for Lactoferrin Binding Protein of <i>Neisseria meningitidis</i>. This protein sequesters iron for the host from Lactoferrin.
  
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===Usage and Biology===
 
  
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<span class='h3bb'>Sequence and Features</span>
 
<span class='h3bb'>Sequence and Features</span>
 
<partinfo>BBa_K1590008 SequenceAndFeatures</partinfo>
 
<partinfo>BBa_K1590008 SequenceAndFeatures</partinfo>
  
  
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===Usage and Biology===
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A majorfound in saliva is a free iron sequestering compound known as lactoferrin, a protein involved in the innate immune system. <i>Neisseria meningitidis</i> is a gram-negative bacterium with an iron-binding outer membrane protein called lactoferrin binding protein A (LbpA). <i>N. meningitidis</i> uses this LbpA to extract iron from the host lactoferrin under pathogenic conditions to allow for the bacterium to perform essential cellular metabolism such as energy generation and DNA replication.
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===Functional Parameters===
 
===Functional Parameters===
 
<partinfo>BBa_K1590008 parameters</partinfo>
 
<partinfo>BBa_K1590008 parameters</partinfo>
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Revision as of 19:28, 18 September 2015

Lactoferrin Binding Protein

Coding sequence for Lactoferrin Binding Protein of Neisseria meningitidis. This protein sequesters iron for the host from Lactoferrin.


Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    INCOMPATIBLE WITH RFC[25]
    Illegal AgeI site found at 172
  • 1000
    COMPATIBLE WITH RFC[1000]


Usage and Biology

A majorfound in saliva is a free iron sequestering compound known as lactoferrin, a protein involved in the innate immune system. Neisseria meningitidis is a gram-negative bacterium with an iron-binding outer membrane protein called lactoferrin binding protein A (LbpA). N. meningitidis uses this LbpA to extract iron from the host lactoferrin under pathogenic conditions to allow for the bacterium to perform essential cellular metabolism such as energy generation and DNA replication.



Functional Parameters