Difference between revisions of "Part:BBa K1611004"

 
Line 1: Line 1:
−
 
 
__NOTOC__
 
__NOTOC__
 
<partinfo>BBa_K1611004 short</partinfo>
 
<partinfo>BBa_K1611004 short</partinfo>
  
−
DEC-205 is an antigen against an endocytic receptor that is expressed by dendritic cells.
+
DEC-205 is an antibody against CD205, an endocytic receptor that is expressed by dendritic cells.
 
Antigen endocytosed via CD205 enters the MHC class I and MHC class II antigen presentation pathways and is subsequently presented to both CD4+ and CD8+ T cells. We used it to activate T-CD8 cells, with tumorous antigen that we binded to.
 
Antigen endocytosed via CD205 enters the MHC class I and MHC class II antigen presentation pathways and is subsequently presented to both CD4+ and CD8+ T cells. We used it to activate T-CD8 cells, with tumorous antigen that we binded to.
  

Revision as of 15:18, 15 September 2015

DEC-205

DEC-205 is an antibody against CD205, an endocytic receptor that is expressed by dendritic cells. Antigen endocytosed via CD205 enters the MHC class I and MHC class II antigen presentation pathways and is subsequently presented to both CD4+ and CD8+ T cells. We used it to activate T-CD8 cells, with tumorous antigen that we binded to.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    INCOMPATIBLE WITH RFC[21]
    Illegal BamHI site found at 533
    Illegal XhoI site found at 414
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]