Difference between revisions of "Part:BBa K1699001"
Line 2: | Line 2: | ||
<partinfo>BBa_K1699001 short</partinfo> | <partinfo>BBa_K1699001 short</partinfo> | ||
− | Human short TERT promoter | + | Human short TERT promoter. |
+ | |||
+ | hTERT (human Telomerase Reverse Transcriptase) is a human promoter which controls the transcription of Telomerase, a gene highly active in cancer cells, and not in healthy ones (1). | ||
Line 20: | Line 22: | ||
<partinfo>BBa_K1699001 SequenceAndFeatures</partinfo> | <partinfo>BBa_K1699001 SequenceAndFeatures</partinfo> | ||
− | + | 1. The telomerase reverse transcriptase promoter drives efficacious tumor suicide gene therapy while preventing hepatotoxicity encountered with constitutive promoters | |
+ | http://www.nature.com/gt/journal/v8/n7/pdf/3301421a.pdf | ||
<partinfo>BBa_K1699001 parameters</partinfo> | <partinfo>BBa_K1699001 parameters</partinfo> | ||
<!-- --> | <!-- --> |
Revision as of 07:34, 3 September 2015
Human short TERT promoter
Human short TERT promoter.
hTERT (human Telomerase Reverse Transcriptase) is a human promoter which controls the transcription of Telomerase, a gene highly active in cancer cells, and not in healthy ones (1).
Usage and Biology
usage and biology
Characterization
characterization
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]
1. The telomerase reverse transcriptase promoter drives efficacious tumor suicide gene therapy while preventing hepatotoxicity encountered with constitutive promoters http://www.nature.com/gt/journal/v8/n7/pdf/3301421a.pdf