Difference between revisions of "Part:BBa K1391011"

 
Line 1: Line 1:
−
 
 
__NOTOC__
 
__NOTOC__
 
<partinfo>BBa_K1391011 short</partinfo>
 
<partinfo>BBa_K1391011 short</partinfo>
Line 6: Line 5:
  
 
Taeho Kim, George S. Vidal, Maya Djurisic, et al. "Human LilrB2 is a beta-amyloid recptor and its murine homolog PirB regulates synaptic plasticity in an Alzheimer's Model". Science. 20 Sep 2013. <http://www.sciencemag.org/content/341/6152/1399>. 16 Oct 2014.
 
Taeho Kim, George S. Vidal, Maya Djurisic, et al. "Human LilrB2 is a beta-amyloid recptor and its murine homolog PirB regulates synaptic plasticity in an Alzheimer's Model". Science. 20 Sep 2013. <http://www.sciencemag.org/content/341/6152/1399>. 16 Oct 2014.
 +
 +
The characterization of the system this is part of can be found in the experience page.
 +
  
  

Revision as of 02:14, 31 October 2014

pENTR_LilrB2

LilrB2 (leukocyte immunoglobin-like receptor B2) is a transmembrane protein found in human neurons shown to bind to beta-amyloid. The interactions is mediated by the first two extracellular immunoglobulin (Ig) domains. Upon binding to beta-amyloid (extracellular), LilrB2 induces enhanced cofilin signaling (intracellular).

Taeho Kim, George S. Vidal, Maya Djurisic, et al. "Human LilrB2 is a beta-amyloid recptor and its murine homolog PirB regulates synaptic plasticity in an Alzheimer's Model". Science. 20 Sep 2013. <http://www.sciencemag.org/content/341/6152/1399>. 16 Oct 2014.

The characterization of the system this is part of can be found in the experience page.



Sequence and Features


Assembly Compatibility:
  • 10
    INCOMPATIBLE WITH RFC[10]
    Illegal EcoRI site found at 603
    Illegal XbaI site found at 529
    Illegal SpeI site found at 1793
    Illegal PstI site found at 1549
    Illegal PstI site found at 1571
  • 12
    INCOMPATIBLE WITH RFC[12]
    Illegal EcoRI site found at 603
    Illegal SpeI site found at 1793
    Illegal PstI site found at 1549
    Illegal PstI site found at 1571
  • 21
    INCOMPATIBLE WITH RFC[21]
    Illegal EcoRI site found at 603
    Illegal BamHI site found at 215
  • 23
    INCOMPATIBLE WITH RFC[23]
    Illegal EcoRI site found at 603
    Illegal XbaI site found at 529
    Illegal SpeI site found at 1793
    Illegal PstI site found at 1549
    Illegal PstI site found at 1571
  • 25
    INCOMPATIBLE WITH RFC[25]
    Illegal EcoRI site found at 603
    Illegal XbaI site found at 529
    Illegal SpeI site found at 1793
    Illegal PstI site found at 1549
    Illegal PstI site found at 1571
    Illegal NgoMIV site found at 820
    Illegal NgoMIV site found at 1513
    Illegal AgeI site found at 352
    Illegal AgeI site found at 852
    Illegal AgeI site found at 1339
  • 1000
    INCOMPATIBLE WITH RFC[1000]
    Illegal SapI.rc site found at 192