Difference between revisions of "Part:BBa K1155000"

 
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__NOTOC__
 
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<partinfo>BBa_K1155000 short</partinfo>
 
<partinfo>BBa_K1155000 short</partinfo>
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<span class='h3bb'>Sequence and Features</span>
 
<span class='h3bb'>Sequence and Features</span>
 
<partinfo>BBa_K1155000 SequenceAndFeatures</partinfo>
 
<partinfo>BBa_K1155000 SequenceAndFeatures</partinfo>
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==='''Characterization'''===
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In ''Escherichia coli'', the switch between aerobic and anaerobic metabolism is partly regulated the transcriptional regulator FNR. This protein has a dual function: it activates genes involved in anaerobic metabolism and represses genes involved in aerobic metabolism. FNR expression is constitutive, but its activity is directly affected by the presence of oxygen which oxidizes of an essential [4Fe-4S] cluster.
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The expression of the ndh gene is repressed by FNR in anaerobic conditions.
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Revision as of 12:41, 4 October 2013

Pndh*

promoter region containing an operator and a promoter controlled by FNR that allow the repression of the downstream gene in anaerobic conditions

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]

Characterization

In Escherichia coli, the switch between aerobic and anaerobic metabolism is partly regulated the transcriptional regulator FNR. This protein has a dual function: it activates genes involved in anaerobic metabolism and represses genes involved in aerobic metabolism. FNR expression is constitutive, but its activity is directly affected by the presence of oxygen which oxidizes of an essential [4Fe-4S] cluster. The expression of the ndh gene is repressed by FNR in anaerobic conditions.