Difference between revisions of "Part:BBa K732001"

 
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<partinfo>BBa_K732001 short</partinfo>
 
<partinfo>BBa_K732001 short</partinfo>
  
A synthetic version of human chorionic gonadotropin (hCG), a hormone produced during pregnancy. The nucleotide sequence was modified to maximize expression efficiency in bacteria and to conform to standard assembly, and the gene was chemically synthesized. The protein coded by this part is the beta subunit of hCG (hCG-&#946;), which contains epitopes recognized by pregnancy tests. The full hCG dimer is also used as an ovulation inducer and can stimulate the production of testosterone in men.
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Human chorionic gonadotropin (hCG) is a hormone produced during pregnancy. Its beta subunit (hCG-β) contains epitopes recognized by pregnancy tests. The full hCG dimer is also used as an ovulation inducer and can stimulate the production of testosterone in men.
  
This sequence can be used to express hCG for any downstream uses, and also as an output signal since it triggers pregnancy tests at low concentrations when properly folded.
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This sequence could ideally be used to express hCG for any downstream uses, and also as an output signal since it could trigger pregnancy tests at low concentrations when properly folded.
  
 
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Latest revision as of 02:10, 1 October 2013

Synthetic Chorionic Gonadotropin, beta (synCG-β)

Human chorionic gonadotropin (hCG) is a hormone produced during pregnancy. Its beta subunit (hCG-β) contains epitopes recognized by pregnancy tests. The full hCG dimer is also used as an ovulation inducer and can stimulate the production of testosterone in men.

This sequence could ideally be used to express hCG for any downstream uses, and also as an output signal since it could trigger pregnancy tests at low concentrations when properly folded.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    INCOMPATIBLE WITH RFC[25]
    Illegal NgoMIV site found at 163
    Illegal NgoMIV site found at 207
  • 1000
    COMPATIBLE WITH RFC[1000]