Difference between revisions of "Part:BBa K1071002"
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− | + | Chloramphenicol interacts with the 50s Subunit of bacterial ribosomes and blocks peptidyltransferase activity. The antibiotic is acting on gram negative as well as on gram positive bacteria. The enzyme Chloramphenicol acetyltransferase (CAT) transfers one or two Acetyl groups to the hydroxyl-Residues of Chloramphenicol. This inactivates the antibiotic. | |
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Revision as of 10:56, 29 September 2013
cat resistance (procaryotic)
Chloramphenicol interacts with the 50s Subunit of bacterial ribosomes and blocks peptidyltransferase activity. The antibiotic is acting on gram negative as well as on gram positive bacteria. The enzyme Chloramphenicol acetyltransferase (CAT) transfers one or two Acetyl groups to the hydroxyl-Residues of Chloramphenicol. This inactivates the antibiotic.
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]