Difference between revisions of "Part:BBa K1019003"

Revision as of 20:56, 27 September 2013

mlrA

MlrA is a transcriptional regulator of the curli operon in an avian pathogenic E. coli strain and in S. enterica subsp. serovar Typhimurium. Its conserved sequence in E. coli K-12 substr. MG1655 is expected to upregulate csgD expression and thus increase biofilm formation.

For further information and extensive references please visit [http://www.ecocyc.org/ECOLI/NEW-IMAGE?type=GENE&object=EG12008 EcoCyc]

References

Brown, P. K., Dozois, C. M., Nickerson, C. A., Zuppardo, A., Terlonge, J., & Curtiss, R. (2001). MlrA, a novel regulator of curli (AgF) and extracellular matrix synthesis by Escherichia coli and Salmonella enterica serovar Typhimurium. Molecular microbiology, 41(2), 349-363.

Ogasawara, H., Yamamoto, K., & Ishihama, A. (2010). Regulatory role of MlrA in transcription activation of csgD, the master regulator of biofilm formation in Escherichia coli. FEMS microbiology letters, 312(2), 160-168.

Sequence and Features

Assembly Compatibility:

10
COMPATIBLE WITH RFC[10]
12
COMPATIBLE WITH RFC[12]
21
INCOMPATIBLE WITH RFC[21]
Illegal BamHI site found at 146
23
COMPATIBLE WITH RFC[23]
25
COMPATIBLE WITH RFC[25]
1000
COMPATIBLE WITH RFC[1000]

@@ Line 1: / Line 1: @@
 __NOTOC__
 <partinfo>BBa_K1019003 short</partinfo>
-mlrA is a transcriptional regulator of the curli operon
+MlrA is a transcriptional regulator of the curli operon in an avian pathogenic ''E. coli'' strain and in ''S. enterica subsp. serovar Typhimurium''. Its conserved sequence in ''E. coli K-12 substr. MG1655'' is expected to upregulate csgD expression and thus increase biofilm formation.
+For further information and extensive references please visit [http://www.ecocyc.org/ECOLI/NEW-IMAGE?type=GENE&object=EG12008 EcoCyc]
+===References===
+Brown, P. K., Dozois, C. M., Nickerson, C. A., Zuppardo, A., Terlonge, J., & Curtiss, R. (2001). MlrA, a novel regulator of curli (AgF) and extracellular matrix synthesis by Escherichia coli and Salmonella enterica serovar Typhimurium. Molecular microbiology, 41(2), 349-363.
+Ogasawara, H., Yamamoto, K., & Ishihama, A. (2010). Regulatory role of MlrA in transcription activation of csgD, the master regulator of biofilm formation in Escherichia coli. FEMS microbiology letters, 312(2), 160-168.
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