Difference between revisions of "Part:BBa K1151000"
LeleBiotec (Talk | contribs) (→Usage and Biology) |
LeleBiotec (Talk | contribs) (→Usage and Biology) |
||
| Line 8: | Line 8: | ||
===Usage and Biology=== | ===Usage and Biology=== | ||
| − | + | [[File:Cattura.jpg]] [[File:Cattura1.jpg]] | |
'''Figure 1:''' HpNikR nickel-binding domain (tetramer). '''Figure 2:''' Proteic sequence analysis with Uniprot. | '''Figure 1:''' HpNikR nickel-binding domain (tetramer). '''Figure 2:''' Proteic sequence analysis with Uniprot. | ||
Revision as of 12:17, 26 September 2013
Nickel-responsive pleiotropic regulator (HpNikR)
The HpNikR protein is a pleiotropic regulator from Helicobacter pylori. In presence of nickel it can acts as an activator or a repressor depending of the specific promoter that contains its operator site. It consists of two dimeric DNA binding domains separated by a tetrameric regulatory domain that binds nickel. This domain corresponds to the C-terminal regulatory domain which contains four nickel binding sites at the tetramer interface. Binding nickel, then a conformational change allows it to activate or repress trascription.
Usage and Biology
Figure 1: HpNikR nickel-binding domain (tetramer). Figure 2: Proteic sequence analysis with Uniprot.
Safety
Sequence and Features
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]