Difference between revisions of "Part:BBa K1151000"

Revision as of 11:51, 26 September 2013

Nickel-responsive pleiotropic regulator (HpNikR)

The HpNikR protein is a pleiotropic regulator from Helicobacter pylori. In presence of nickel it can acts as an activator or a repressor depending of the specific promoter that contains its operator site. It consists of two dimeric DNA binding domains separated by a tetrameric regulatory domain that binds nickel. This domain corresponds to the C-terminal regulatory domain which contains four nickel binding sites at the tetramer interface. Binding nickel, then a conformational change allows it to activate or repress trascription.

Usage and Biology

HOLO-NI(II) HPNIKR TETRAMER.

Sequence and Features

Assembly Compatibility:

10
COMPATIBLE WITH RFC[10]
12
COMPATIBLE WITH RFC[12]
21
COMPATIBLE WITH RFC[21]
23
COMPATIBLE WITH RFC[23]
25
COMPATIBLE WITH RFC[25]
1000
COMPATIBLE WITH RFC[1000]

Revision as of 11:50, 26 September 2013 (view source) LeleBiotec (Talk \| contribs) (→‎Usage and Biology) ← Older edit		Revision as of 11:51, 26 September 2013 (view source) LeleBiotec (Talk \| contribs) (→‎Usage and Biology) Newer edit →
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	HOLO-NI(II) HPNIKR TETRAMER.		HOLO-NI(II) HPNIKR TETRAMER.