Difference between revisions of "Part:BBa K801091"

(Background and principles)
(References)
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=References=
 
=References=
 
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[http://www.ncbi.nlm.nih.gov/pubmed/15932991 '''Pubmed''' : Jiang, H., Wood, K.V., Morgan, J.A., 2005. Metabolic Engineering of the Phenylpropanoid Pathway in Saccharomyces cerevisiae. Appl. Environ. Microbiol. 71, 2962–2969]
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*[[http://www.ncbi.nlm.nih.gov/pubmed/12481418 Gerhauser et al., 2002]] Gerhauser, C., Alt, A., Heiss, E., Gamal-Eldeen, A., Klimo, K., Knauft, J., Neu- mann, I., Scherf, H.-R., Frank, N., Bartsch, H., and Becker, H. (2002). Cancer chemopreventive activity of xanthohumol, a natural product derived from hop. ''Mol Cancer Ther'', 1(11):959–69.
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*[[http://www.ncbi.nlm.nih.gov/pubmed/10752639 Henderson et al., 2000]] Henderson, M. C., Miranda, C. L., Stevens, J. F., Deinzer, M. L., and Buhler, D. R. (2000). In vitro inhibition of human p450 enzymes by prenylated flavonoids from hops, ''humulus lupulus''. ''Xenobiotica'', 30(3):235–51.
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*[[http://www.ncbi.nlm.nih.gov/pubmed/14704995 Jiang and Morgan, 2004]] Jiang, H. and Morgan, J. A. (2004). Optimization of an in vivo plant p450 monooxygenase system in ''Saccharomyces cerevisiae''. ''Biotechnol Bioeng'', 85(2):130–7.
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*[[http://www.ncbi.nlm.nih.gov/pubmed/10737704 Miranda et al., 2000a]] Miranda, C. L., Aponso, G. L., Stevens, J. F., Deinzer, M. L., and Buhler, D. R. (2000a). Prenylated chalcones and flavanones as inducers of quinone reductase in mouse hepa 1c1c7 cells. ''Cancer Lett'', 149(1-2):21–9.
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*[[http://www.ncbi.nlm.nih.gov/pubmed/10418944 Miranda et al., 1999]] Miranda, C. L., Stevens, J. F., Helmrich, A., Henderson, M. C., Rodriguez, R. J., Yang, Y. H., Deinzer, M. L., Barnes, D. W., and Buhler, D. R. (1999). Antiproliferative and cytotoxic effects of prenylated flavonoids from hops (''Humulus lupulus'') in human cancer cell lines. ''Food Chem Toxicol'', 37(4):271–85.
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*[[http://www.ncbi.nlm.nih.gov/pubmed/10995285 Miranda et al., 2000b]] Miranda, C. L., Stevens, J. F., Ivanov, V., McCall, M., Frei, B., Deinzer, M. L., and Buhler, D. R. (2000b). Antioxidant and prooxidant actions of prenylated and nonprenylated chalcones and flavanones in vitro. ''J Agric Food Chem'', 48(9):3876–84.
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*[[http://www.ncbi.nlm.nih.gov/pubmed/11038156 Miranda et al., 2000c]] Miranda, C. L., Yang, Y. H., Henderson, M. C., Stevens, J. F., Santana-Rios, G., Deinzer, M. L., and Buhler, D. R. (2000c). Prenylflavonoids from hops inhibit the metabolic activation of the carcinogenic heterocyclic amine 2-amino-3-methylimidazo[4, 5-f]quinoline, mediated by cdna-expressed human cyp1a2. ''Drug Metab Dispos'', 28(11):1297–302.
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*[[http://www.ncbi.nlm.nih.gov/pubmed/19631278 Trantas et al., 2009]] Trantas, E., Panopoulos, N., and Ververidis, F. (2009). Metabolic engineering of the complete pathway leading to heterologous biosynthesis of various flavonoids and stilbenoids in ''Saccharomyces cerevisiae''. ''Metab Eng'', 11(6):355–66.
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*[[http://www.ncbi.nlm.nih.gov/pubmed/11240137 Yilmazer et al., 2001a]] Yilmazer, M., Stevens, J. F., and Buhler, D. R. (2001a). In vitro glucuronidation of xanthohumol, a flavonoid in hop and beer, by rat and human liver microsomes. ''FEBS Lett'', 491(3):252–6.
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*[[http://www.ncbi.nlm.nih.gov/pubmed/11181488 Yilmazer et al., 2001b]] Yilmazer, M., Stevens, J. F., Deinzer, M. L., and Buhler, D. R. (2001b). In vitro biotransformation of xanthohumol, a flavonoid from hops (''Humulus lupulus''), by rat liver microsomes. ''Drug Metab Dispos'', 29(3):223–31.

Revision as of 12:44, 16 October 2012

phenylalanine ammonia lyase (PAL) coding region

Coding region for the enzyme phenylalanine ammonia lyase (PAL) from Rhodosporidium toruloides

Background and principles

Structure of Xanthohumol

Usage and Biology

















Biosynthesis

text text





















Characterization


Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    INCOMPATIBLE WITH RFC[21]
    Illegal BglII site found at 2090
    Illegal BamHI site found at 352
    Illegal XhoI site found at 403
    Illegal XhoI site found at 466
    Illegal XhoI site found at 484
    Illegal XhoI site found at 562
    Illegal XhoI site found at 763
    Illegal XhoI site found at 1006
    Illegal XhoI site found at 1753
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    INCOMPATIBLE WITH RFC[25]
    Illegal NgoMIV site found at 922
    Illegal NgoMIV site found at 1168
    Illegal NgoMIV site found at 1336
    Illegal NgoMIV site found at 1479
    Illegal NgoMIV site found at 1813
  • 1000
    INCOMPATIBLE WITH RFC[1000]
    Illegal BsaI site found at 463
    Illegal BsaI site found at 793
    Illegal BsaI site found at 799
    Illegal BsaI.rc site found at 1924
    Illegal SapI site found at 753


References