Difference between revisions of "Part:BBa K639002:Experience"

Latest revision as of 08:57, 26 August 2011

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Applications of BBa_K639002

Previous studies have shown that the rrnB P1 promoter is downregulated by ppGpp [1], which is an alarmone involved in the stringent response in bacteria. Our project involved using the rrnB P1 promoter as a stress-sensor, where it would stop expressing an inhibitor for a second promoter, thus giving a signal.

[1] Magnusson, Lisa U., Farewell, Anne, Nyström, Thomas: "ppGpp: a global regulator in Escherichia Coli", 2005

User Reviews

UNIQeb5b00e089f0a156-partinfo-00000000-QINU UNIQeb5b00e089f0a156-partinfo-00000001-QINU

Revision as of 08:50, 26 August 2011 (view source) Espenban (Talk \| contribs) (→‎Applications of BBa_K639002) ← Older edit		Latest revision as of 08:57, 26 August 2011 (view source) Espenban (Talk \| contribs) (→‎Applications of BBa_K639002)
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	===Applications of BBa_K639002===		===Applications of BBa_K639002===

−	Previous studies have shown that the rrnB P1 promoter is downregulated by ppGpp [1], which is an alarmone involved in the stringent response in bacteria.	+	Previous studies have shown that the rrnB P1 promoter is downregulated by ppGpp [1], which is an alarmone involved in the stringent response in bacteria. Our project involved using the rrnB P1 promoter as a stress-sensor, where it would stop expressing an inhibitor for a second promoter, thus giving a signal.