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  • Part:BBa K4701306
    ===TPA assimilation pathway=== ...e pathway continues towards central metabolism via the PCA-3,4-dioxygenase pathway [6].
    5 KB (722 words) - 11:25, 31 August 2023
  • Part:BBa K5226061
    ...can metabolize formate. We chose to <b>introduce the formate assimilation pathway</b> to enable it to utilize formate, a difficult-to-recover product in CDE. The construct referred to as C1M is part of the formate assimilation pathway and consists of three key enzymes: <b>formate-tetrahydrofolate ligase, meth
    4 KB (644 words) - 16:39, 30 September 2024
  • Part:BBa K5226063
    ...can metabolize formate. We chose to <b>introduce the formate assimilation pathway</b> to enable it to utilize formate, a difficult-to-recover product in CDE. ..."https://static.igem.wiki/teams/5226/parts/pathway-of-formate-assimilation-pathway.png" width="700px">
    6 KB (855 words) - 02:40, 1 October 2024
  • Part:BBa K2971002
    ...(CrtB). Phytoene synthase catalyzes the first reaction in the biosynthetic pathway of 1. Liu, C., Sun, Z., Shen, S., Lin, L., Li, T., Tian, B., & Hua, Y. (2014). Identification and characterization of the geranylge
    3 KB (432 words) - 00:08, 22 October 2019
  • Part:BBa K4165083
    ...to be located extracellularly which interferes with the TGF-β signalling pathway. The inhibitor binds to trypsin-like (serine) proteases and since the catal 2 - Grau, S., Baldi, A., Bussani, R., Tian, X., Stefanescu, R., Przybylski, M., ... & Ehrmann, M. (2005). Implications
    3 KB (372 words) - 12:40, 13 October 2022
  • Part:BBa K5313021:Design
    ...hylation along with other enzymes such as NdmC and NdmD. The N-demethylase pathway in Pseudomonas CBB5 is one of the few naturally occurring mechanisms of caf [2] Liu J, Tian J, Perry C, Lukowski AL, Doukov TI, Narayan ARH, Bridwell-Rabb J. Design pr
    3 KB (395 words) - 05:53, 1 October 2024
  • Part:BBa J428074
    ...bber‐enriched dandelion varieties by metabolic engineering of the inulin pathway. In Plant Biotechnology Journal (Vol. 15, Issue 6, pp. 740–753). Wiley. h
    18 KB (2,654 words) - 22:10, 1 October 2024
  • Part:BBa K5226074
    ...can metabolize formate. We chose to <b>introduce the formate assimilation pathway</b> to enable it to utilize formate, a difficult-to-recover product in CDE. ...et al. Growth of E. coli on formate and methanol via the reductive glycine pathway[J]. Nature chemical biology, 2020, 16(5): 538-545.
    6 KB (887 words) - 03:16, 1 October 2024
  • Part:BBa K2976009
    ...d with an NF-&#954;B inducible promoter to responsively promote downstream pathway designed, the normol cells can release granulysin to destroy <i>Mtb</i> in ..., and with an NF-κB inducible promoter to responsively promote downstream pathway designed, the normol cells can release granulysin to destroy Mtb in the blo
    7 KB (1,060 words) - 10:09, 9 December 2020
  • Part:BBa K4743000
    ...tyrosine to produce fumarate and homogentisate in the tyrosine degradation pathway. However, the gene HPD plays another crucial role in team iGEM23_PTSH-Taiwa <span class='h3bb'><big>'''Overall metabolic pathway of HMB'''</big></span>
    2 KB (290 words) - 13:37, 4 October 2023
  • Part:BBa K5044044
    ...ascorbate in fruits and tubers through over-expression of the L-galactose pathway gene GDP-L-galactose phosphorylase. Plant Biotechnol J 10:390–397. http:/ ...rcher D, Ruf S, Bock R (2017) Horizontal transfer of a synthetic metabolic pathway between plant species. Curr Biol 27:3034–3041. http://doi.org/10.1016/j.c
    35 KB (4,884 words) - 13:25, 2 October 2024
  • Part:BBa K1696001
    ...ation. The glucose is converted to pyruvate via the Embden-Meyerhof-Parnas pathway, and in the final step pyruvate is reduced to two isomeric forms of lactic ...by an NAD+-dependent L-lactate dehydrogenase (ldhA)[2]. Similar metabolic pathway has been found in a variety of organisms, to distinguish the differences, w
    2 KB (236 words) - 13:48, 17 September 2015
  • Part:BBa K4829008
    ...l transducer and activator of transcription 3 (STAT3) pathway and the MAPK pathway. * Tian, J., Chen, X., Fu, S. et al. Bazedoxifene is a novel IL-6/GP130 inhibitor f
    8 KB (1,094 words) - 19:13, 11 October 2023
  • Part:BBa K4829009
    ...l transducer and activator of transcription 3 (STAT3) pathway and the MAPK pathway. * Tian, J., Chen, X., Fu, S. et al. Bazedoxifene is a novel IL-6/GP130 inhibitor f
    8 KB (1,262 words) - 19:15, 11 October 2023
  • CRISPR
    ...reatment of tuberculosis. 1) We are reproducing an essential MTb metabolic pathway in E. coli, where it can be easily and safely targeted in a drug screen. 2) <li>Quan, J., & Tian, J. (2009). Circular polymerase extension cloning of complex gene libraries
    43 KB (6,626 words) - 15:52, 16 July 2020
  • Part:BBa K2976004
    ...agonist to stimulate Toll like receptor (TLR) and its downstream signaling pathway. In our project, the activation of NF-κB can eventually leads to the expre <p>[4] Ma, J. , Lu, J. , Huang, H. , Teng, X. , Tian, M. , & Yu, Q. , et al. (2015). Inhalation of recombinant adenovirus expres
    5 KB (663 words) - 22:14, 21 October 2019
  • Part:BBa K2971000
    GGPP is a precursor for the carotenoid biosynthetic pathway. The sequence has been codon optimized 1. Liu, C., Sun, Z., Shen, S., Lin, L., Li, T., Tian, B., & Hua, Y. (2014). Identification and characterization of the geranylge
    3 KB (441 words) - 00:07, 22 October 2019
  • Part:BBa K4160007
    ...AT-induced IL-10 will be expressed and secreted via the JAK/STAT signaling pathway. In the project of TU-Eindhoven 2022, IL-10 will act as the therapeutic age <li>Tian G, Li JL, Wang DG, Zhou D. Targeting IL-10 in Auto-immune Diseases. Cell Bi
    4 KB (533 words) - 14:10, 11 October 2022
  • Part:BBa K4701306:Design
    <i>Comamonas</i> sp. E6 contains a known TPA assimilation pathway enabled by two highly similar operons: <i>tph<sub>I</sub></i> and <i>tph<su [4] Tian, T, Salis, HM. et al. (2015) A predictive biophysical model of translationa
    19 KB (2,894 words) - 12:35, 31 August 2023
  • Part:BBa K4601201
    ...Pulver SR, Birdsey-Benson A, Cho YK, Morimoto TK, Chuong AS, Carpenter EJ, Tian Z, Wang J, Xie Y, Yan Z, Zhang Y, Chow BY, Surek B, Melkonian M, Jayaraman ...t I, Maranas CD, Salis HM. Rational design of a synthetic Entner-Doudoroff pathway for improved and controllable NADPH regeneration. Metabolic Engineering (20
    39 KB (5,937 words) - 10:18, 12 October 2023

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