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  • ...d with an NF-&#954;B inducible promoter to responsively promote downstream pathway designed, the normol cells can release granulysin to destroy <i>Mtb</i> in ..., and with an NF-κB inducible promoter to responsively promote downstream pathway designed, the normol cells can release granulysin to destroy Mtb in the blo
    7 KB (1,060 words) - 10:09, 9 December 2020
  • ...in the surrounding of the cell via the Toll-like receptor, NF-&#954;B/AP1 pathway leading to strong induction of gene expression. Due to its relatively low b ...detecting LPS in the surrounding of the cell via the TLR4-NF-&#954;B/c-Jun pathway leading to enhanced gene expression. It is much more sensitive than the nat
    8 KB (1,265 words) - 16:53, 27 October 2020
  • ...in the surrounding of the cell via the Toll-like receptor, NF-&#954;B/AP1 pathway leading to strong induction of gene expression. Due to its high basal activ ...detecting LPS in the surrounding of the cell via the TLR4-NF-&#954;B/c-Jun pathway leading to enhanced gene expression. It is much more sensitive than the nat
    9 KB (1,340 words) - 16:56, 27 October 2020
  • <p> JTi2 can also be applied as a NF-κB pathway reporter promoter.</p> ...ur necrosis factor receptor(TNFR) thus activates its downstream signalling pathway through which NF-κB can be released. The TNFR-IKK-NF-κB cascade is one of
    4 KB (646 words) - 18:54, 25 October 2020
  • ...ances of <i>M.tuberculosis</i> and then stimulate the downstream signaling pathway. Then, activated NF-κB initiates transcription of the gene circuits to exp ...analysis of TLR1, TLR2 and CD14 expression and activation of TLR signaling pathway.]]
    5 KB (761 words) - 00:39, 22 October 2019
  • ...nsducted by Toll like receptors, once the protein at the downstream of the pathway, NF-κB, senses the signal, it will be activated and enter into the nucleus ...the phosphorylation of IκB increased,indicating the promotion of NF-κB pathway.]]
    4 KB (539 words) - 21:48, 21 October 2019
  • ...e the substances of <i>Mtb</i> and then stimulate the downstream signaling pathway. Then, activated NF-&#954;B initiates transcription of the gene circuits to ...''Western blot analysis of TLR2 expression and activation of TLR signaling pathway.]]
    5 KB (777 words) - 17:50, 23 October 2020
  • ...e the substances of <i>Mtb</i> and then stimulate the downstream signaling pathway. Then, activated NF-&#954;B initiates transcription of the gene circuits to ...''Western blot analysis of TLR1 expression and activation of TLR signaling pathway.]]
    5 KB (731 words) - 17:51, 23 October 2020
  • ...ecognize the substances of Mtb and then stimulate the downstream signaling pathway. Then, activated NF-&#954;B initiates transcription of the gene circuits to
    3 KB (372 words) - 18:27, 20 October 2020
  • ...une responses to <i>Mtb</i> via control of A20, an inhibitor of the NF-κB pathway. The Nuclear factor-kappa B (NF-κB) family of transcription factor plays a ...-(Lys)4, TLR1/TLR2 agonist to stimulate Toll like receptor (TLR) signaling pathway. In our project, the activation of NF-κB can eventually leads to the expre
    5 KB (696 words) - 21:24, 21 October 2019
  • ...he NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) pathway.[1] In the NF-κB pathway, IKKβ phosphorylates the IkB inhibitory protein, a process which enables t
    2 KB (355 words) - 17:34, 12 October 2018
  • ...he NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) pathway.[1] In the NF-κB pathway, IKKβ phosphorylates the IkB inhibitory protein, a process which enables t
    2 KB (353 words) - 10:46, 13 October 2018
  • ...he NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) pathway.[1] In the NF-κB pathway, IKKβ phosphorylates the IkB inhibitory protein, a process which enables t
    2 KB (352 words) - 10:53, 13 October 2018
  • ...he NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) pathway.[1] In the NF-κB pathway, IKKβ phosphorylates the IkB inhibitory protein, a process which enables t
    2 KB (352 words) - 11:18, 13 October 2018
  • NF-κB has been considered a prototypical proinflammatory signaling pathway. This is based on the activation of NF-κB by proinflammatory cytokines suc <p>1. Lawrence T. (2009). The nuclear factor NF-kappaB pathway in inflammation. Cold Spring Harbor perspectives in biology, 1(6), a001651.
    1 KB (205 words) - 17:42, 23 October 2020
  • ...y toxin sensors (Kawai and Akira 2007). In this study we used the LPS-TLR4 pathway to characterize our synthetic sensor. Since IL-6 promoter activity cannot b
    9 KB (1,325 words) - 17:21, 27 October 2020
  • ...y toxin sensors (Kawai and Akira 2007). In this study we used the LPS-TLR4 pathway to characterize our synthetic sensor. Since IL-6 promoter activity cannot b
    8 KB (1,207 words) - 00:10, 27 October 2020
  • ...une responses to <i>Mtb</i> via control of A20, an inhibitor of the NF-κB pathway, which plays an essential role in regulating the expression of pro-inflamma
    4 KB (567 words) - 01:24, 22 October 2019
  • ...eptor subunit also shared by many other cytokines. The classical signaling pathway is triggered by the hemerer complex formed by mIL-6R. ...gen-activated protein kinase) pathway and the gp130 YXXQ-mediated JAK/STAT pathway (Figure 2) [7].
    8 KB (1,248 words) - 12:55, 4 October 2021
  • ...inflammatory mediators. Furthermore, melittin interferes with the JAK/STAT pathway, inhibiting the activity of STAT transcription factors decreasing the secre ...a a reactive oxygen species (ROS)-mediated mitochondrial/caspase-dependent pathway, inhibiting fungal growth. It also inhibits the activity of (1,3)-β-D-gluc
    13 KB (1,779 words) - 13:25, 2 October 2024

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