Protein coding sequences/Biosynthesis/Isoprenoids

< Back to Biosynthesis Protein coding sequences

Isoprenoids, also known as terpenoids, are a large and highly diverse class of natural organic chemicals with many functions in plant primary and secondary metabolism. Most are multicyclic structures that differ from one another not only in functional groups but also in their basic carbon skeletons. Isoprenoids are synthesized from common prenyl diphosphate precursors through the action of terpene synthases and terpene-modifying enzymes such as cytochrome P450 monooxygenases. Plant terpenoids are used extensively for their aromatic qualities. They play a role in traditional herbal remedies and are under investigation for antibacterial, antineoplastic, and other pharmaceutical functions. Much effort has been directed toward their production in microbial hosts.

There are two primary pathways for making isoprenoids: the mevalonate pathway and the non-mevalonate pathway.


More...
NameProteinDescriptionDirectionUniprotKEGGE.C.SubstrateProductLengthStatus
BBa_K118000 dxs coding sequence encoding 1-deoxyxylulose-5-phosphate synthase     1866In stock
BBa_K118002 crtB coding sequence encoding phytoene synthase     933In stock
BBa_K118003 crtI coding sequence encoding phytoene dehydrogenase     1482In stock
BBa_K118008 crtY coding sequence encoding lycopene B-cyclase     1152In stock
BBa_K849000 3-Hydroxy-3-Methyl-Glutaryl-CoA-Reductase from Yeast     1584In stock
BBa_K849003 bifunctional Cyclase from Gibberella fujikuroi     2859In stock
BBa_K849004 ent-Kaurene Oxidase from Gibberella fujikuroi     1578In stock
BBa_K115050 A-coA -> AA-coA     1188It's complicated
BBa_K115056 IPP -> OPP or DMAPP -> OPP     552It's complicated
BBa_K115057 OPP -> FPP     903It's complicated
BBa_K343001 B-carotene monooxygenase, Produces retinal from B-carotene. ninaB gene from Drosophila. Dmel_CG9347   1863It's complicated
BBa_K849001 Farnesyl-Pyrophosphate-Synthase from Yeast     1059It's complicated