Coding

Part:BBa_K5083003:Design

Designed by: Jiayi Chen   Group: iGEM24_Squirrel-CHN   (2024-08-25)


DPP-4 Protein Inhibitor


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


Design Notes

Source

De novo protein design by AI

References

[1] Abramson J, Adler J, Dunger J, et al. Accurate structure prediction of biomolecular interactions with AlphaFold 3[J]. Nature, 2024: 1-3. [2] Baek M, DiMaio F, Anishchenko I, et al. Accurate prediction of protein structures and interactions using a three-track neural network[J]. Science, 2021, 373(6557): 871-876. [3] Dauparas J, Anishchenko I, Bennett N, et al. Robust deep learning–based protein sequence design using ProteinMPNN[J]. Science, 2022, 378(6615): 49-56. [4] Watson J L, Juergens D, Bennett N R, et al. De novo design of protein structure and function with RFdiffusion[J]. Nature, 2023, 620(7976): 1089-1100. [5] Krishna R, Wang J, Ahern W, et al. Generalized biomolecular modeling and design with RoseTTAFold All-Atom[J]. Science, 2024, 384(6693): eadl2528.