Coding

Part:BBa_K4653101:Design

Designed by: Tangkun Zhu   Group: iGEM23_SZU-China   (2023-10-06)


PehA


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    INCOMPATIBLE WITH RFC[25]
    Illegal NgoMIV site found at 209
    Illegal NgoMIV site found at 799
    Illegal NgoMIV site found at 1297
    Illegal NgoMIV site found at 1330
    Illegal NgoMIV site found at 1469
    Illegal NgoMIV site found at 1519
  • 1000
    INCOMPATIBLE WITH RFC[1000]
    Illegal BsaI site found at 571
    Illegal SapI.rc site found at 622


Design Notes

PehA is a polygalacturonic endonuclide derived from Ralstonia solanacearum. It can recognize and cut polygalacturonic acid in pectin of plant cell wall to produce oligogalacturonic acid (OG), which is recognized by pattern recognition receptors on the surface of plant cell membrane and stimulates plant immunity.


Source

Ralstonia solanacearum.

References

[1] Kohorn B D, Kohorn S L. The cell wall-associated kinases, WAKs, as pectin receptors[J]. Frontiers in plant science, 2012, 3: 88.
[2] Ferrari S, Savatin DV, Sicilia F, Gramegna G, Cervone F, Lorenzo GD. Oligogalacturonides: plant damage-associated molecular patterns and regulators of growth and development. Front Plant Sci. 2013 Mar 13;4:49. doi: 10.3389/fpls.2013.00049.
[3] Huang Q, Allen C. Polygalacturonases are required for rapid colonization and full virulence of Ralstonia solanacearum on tomato plants[J]. Physiological and molecular plant pathology, 2000, 57(2): 77-83.
[4] Huang Q, Allen C. Polygalacturonases are required for rapid colonization and full virulence of Ralstonia solanacearum on tomato plants[J]. Physiological and molecular plant pathology, 2000, 57(2): 77-83.
[5] Oligogalacturonides: plant damage-associated molecular patterns and regulators of growth and development