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S. cerevisiae, a species of budding yeast, is a convenient chassis for engineered biological systems for several reasons.

  • It is one of the most intensively studied eukaryotic model organisms in molecular and cell biology.
  • As a single celled organism S. cerevisiae is small with a short generation time (doubling time 1.5–2 hours at 30°C) and can be easily cultured.
  • S. cerevisiae can be transformed allowing for either the addition of new genes or deletion through homologous recombination. Furthermore, The ability to grow S. cerevisiae as a haploid simplifies the creation of gene knockouts strains.
  • As a eukaryote, S. cerevisiae shares the complex internal cell structure of plants and animals without the high percentage of non-coding DNA that can confound research in higher eukaryotes.

As an aside, it is perhaps the most useful yeast owing to its use since ancient times in baking and brewing.

To flag a part as being functional in yeast, add "//chassis/eukaryote/yeast" to the Categories section under "Hard Information" of a part.