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S. cerevisiae, a species of budding yeast, is a convenient chassis for engineered biological systems for several reasons.

  • It is one of the most intensively studied eukaryotic model organisms in molecular and cell biology.
  • As a single celled organism S. cerevisiae is small with a short generation time (doubling time 1.5–2 hours at 30°C) and can be easily cultured.
  • S. cerevisiae can be transformed allowing for either the addition of new genes or deletion through homologous recombination. Furthermore, The ability to grow S. cerevisiae as a haploid simplifies the creation of gene knockouts strains.
  • As a eukaryote, S. cerevisiae shares the complex internal cell structure of plants and animals without the high percentage of non-coding DNA that can confound research in higher eukaryotes.

As an aside, it is perhaps the most useful yeast owing to its use since ancient times in baking and brewing.

  • [ The Yeast Genome database] is a highly curated database of information regarding yeast.

To flag a part as being functional in yeast, add "//chassis/eukaryote/yeast" to the Categories section under "Hard Information" of a part.