File:TU Eindhoven Strain-Promoted Azide-Alkyne Cycloaddition.png

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Strain-promoted Azide-Alkyne Cycloaddition (SPAAC) is a well known click-chemistry reaction. The reaction features two molecules, one functionalized with an azide group (A) and one functionalized with a cyclooctyne group (B). SPAAC is very efficient and selective, no further reagents have to be added to the reaction method and the reaction is completely bio-orthogonal. This image was adapted from iGEM TU Eindhoven 2014 team’s wiki.

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current10:00, 15 September 2015Thumbnail for version as of 10:00, 15 September 20151,000 × 172 (44 KB)S136969 (Talk | contribs)Strain-promoted Azide-Alkyne Cycloaddition (SPAAC) is a well known click-chemistry reaction. The reaction features two molecules, one functionalized with an azide group (A) and one functionalized with a cyclooctyne group (B). SPAAC is very efficient and s
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