File:T--William and Mary--LacIAM.png

"Each genetically encoded sensor is shown, with coding (red) and non-coding (grey/black) mutations noted. Mutations in grey were also applied to the parental sensor. The corresponding response functions comparing the evolved (blue) and parental (grey) sensors. The fit of Equation 1 to the mean of three replicates performed on different days is shown (see Supplementary Figure 5 for data). The response function parameters for evolved sensors are provided in Table 1."^{1 1}Meyer, A. J., Segall-Shapiro, T. H., & Voigt, C. A. (2018). Marionette: E. coli containing 12 highly-optimized small molecule sensors. BioRxiv, 285866. doi:https://doi.org/10.1101/285866