HB-EGF/Tar Receptor (HT) Device
This part is a chimeric between extracellular (binding) domain of Homo sapiens heparin-binding EGF-like growth factor (HB-EGF) receptor and transmembrane/intracellular domain of Escherichia coli Tar chemotaxis receptor.
Usage and Biology
This part can be used to detect diphtheria toxin as it has HB-EGF binding domain. It also can activate chemotaxis pathway in E. coli upon receptor activation as it has Tar transmembrane/intracellular domain.
Sequence and Features
- 10COMPATIBLE WITH RFC
- 12COMPATIBLE WITH RFC
- 21COMPATIBLE WITH RFC
- 23COMPATIBLE WITH RFC
- 25Illegal AgeI site found at 1294
- 1000Illegal BsaI site found at 1434