Protein_Domain

Part:BBa_K2607000

Designed by: Andrea Laurentius   Group: iGEM18_UI_Indonesia   (2018-09-25)


DiphTox (DT)

This part is a modified synthetic Corynebacterium diphtheriae exotoxin consisting of only domain responsible for binding with its receptor, heparin-binding epidermal growth factor-like growth factor (HB-EGF).

Usage and Biology

This part can be used as a 'safe' model to study diphtheria toxin interaction with HB-EGF receptor, or chimeric between HB-EGF with another receptors.

Sequence and Features

Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


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Categories
Parameters
None