Protein domains/Linker

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Linkers are short peptide sequences that occur between protein domains. Linkers are often composed of flexible residues like glycine and serine so that the adjacent protein domains are free to move relative to one another. Longer linkers are used when it is necessary to ensure that two adjacent domains do not sterically interfere with one another.


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NameDescriptionAA sequenceLength
BBa_J176131PLrigid 60
BBa_J189202aa GS linker  6
BBa_J189216aa [GS]x linker  18
BBa_J1892210aa [GS]x linker 30
BBa_K10501210 aa flexible protein domain linker  30
BBa_K1331328 aa protein domain linker 24
BBa_K1486003Flexible linker 2x (GGGS) 24
BBa_K1486004flexible linker 2x (GGGGS) 30
BBa_K148603713 amino acids linker [GGGS GGGGS GGGS] 39
BBa_K148605310 aa linker 30
BBa_K157009Split fluorophore linker; Freiburg standard 51
BBa_K15701315 aa flexible glycine-serine protein domain linker; Freiburg standard 45
BBa_K243004Short Linker (Gly-Gly-Ser-Gly) 12
BBa_K243005Middle Linker ( Gly-Gly-Ser-Gly)x2 24
BBa_K243006Long Linker (Gly-Gly-Ser-Gly)x3 36
BBa_K243029GSAT Linker 108
BBa_K243030SEG 108
BBa_K404300SEG-Linker 108
BBa_K404301GSAT-Linker 108
BBa_K404303Z-EGFR-1907_Short-Linker  192
BBa_K404304Z-EGFR-1907_Middle-Linker  204
BBa_K404305Z-EGFR-1907_Long-Linker  216
BBa_K404306Z-EGFR-1907_SEG-Linker  288
BBa_K416001(Gly4Ser)3 Flexible Peptide Linker 45
BBa_K648005Short Fusion Protein Linker: GGSG with standard 25 prefix/suffix 12
BBa_K648006Long 10AA Fusion Protein Linker with Standard 25 Prefix/Suffix 30
BBa_K648007Medium 6AA Fusion Protein Linker: GGSGGS with Standard 25 Prefix/Suffix 18


References

BiblioPlus Extension Error fetching PMID 2313701:
Error fetching PMID 10835103:
Error fetching PMID 12538906:
Error fetching PMID 11579220:
  1. Error fetching PMID 2313701: [Argos]
  2. Error fetching PMID 10835103: [Crasto]
  3. Error fetching PMID 12538906: [George]
  4. Error fetching PMID 11579220: [Arai]
All Medline abstracts: PubMed | HubMed