DNA

Part:BBa_M11056

Designed by: sanjib kumar shrestha   Group: UtahState BE5930 - S09 UtahState BE5930 - S10   (2009-04-16)


neo6 gene

2-deoxystraptamine(2-DOS) is a core aglycon that is the vital to backbone formation in various aminoglycoside. This core structure can be modified to develop hybrid types of amninoglycoside antibiotics. There is a single open reading frame in the Streptomyces fradiae genome, that contains three genes neo7,neo6 and neo5. These genes work in concert to produce 2-deoxystraptamine compound. The neo6 gene encodes the enzyme called L-glutamine:2-deoxy-scyllo-inosose aminotransferase which plays vital role in the biosynthesis of the core aglycon, 2-DOS.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    INCOMPATIBLE WITH RFC[25]
    Illegal NgoMIV site found at 232
    Illegal NgoMIV site found at 271
    Illegal NgoMIV site found at 577
  • 1000
    INCOMPATIBLE WITH RFC[1000]
    Illegal BsaI site found at 3
    Illegal BsaI.rc site found at 739


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Categories
Parameters
None