Composite

Part:BBa_K3851001

Designed by: Max Swann   Group: iGEM21_Baltimore_BioCrew   (2021-08-28)


TPH1 gene from Homo sapiens codon-optimized for E. coli with constitutive promoter

The TPH1 gene in humans uses L-tryptophan to produce 5-HTP, the biochemical precursor to serotonin. Serotonin reduces the effects of depression and anxiety. Increased expression levels of TPH1 can alleviate or eliminate depressive symptoms, but a negative feedback loop is recommended to prevent over-expression. -source (bba and team) -codon-optimized -check for restriction sites -add regulatory sequences (names and part numbers; any additional info about why they were chosen)


Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


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Parameters
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