Help:Promoters/Bacteriophage RNAP
This page provides information about bacteriophage RNA polymerases (RNAP). For example, how many subunits are in a particular RNAP, how does the RNAP recognize promoters or what is the consensus promoter sequences for a particular promoter.
T7 RNAP
A 3d structure for T7 RNAP (blue) transcribing DNA (orange) to produce mRNA (green). Image obtained from http://www.molecularstation.com/molecular-biology-images/502-dna-pictures/42-t7-rna-polymerase.html?size=big.
T7 RNAP is a single-subunit RNA polymerase from bacteriophage T7. The nucleotide sequence for T7 RNAP is known and available from the registry (see BBa_I2032). T7 RNAP is known to be highly active and is also a highly selective RNAP. The consensus promoter sequence for T7 RNAP is represented by the sequence logos shown below.
